We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Ultrasound Catheter Offers New Treatment Option for Hypertension

By MedImaging International staff writers
Posted on 10 Mar 2023
Print article
Image: The Paradise ultrasound denervation device (Photo courtesy of ReCor Medical)
Image: The Paradise ultrasound denervation device (Photo courtesy of ReCor Medical)

For patients diagnosed with hypertension, the typical course of treatment involves lifestyle modifications, such as reducing salt intake and losing weight, coupled with medications to reduce blood pressure. Nevertheless, despite these interventions, approximately one-third of hypertensive patients are unable to regulate their blood pressure. This can lead to detrimental consequences, such as heart failure, strokes, heart attacks, and irreversible kidney damage. Now, a device that employs ultrasound-based technology to calm overactive nerves in the kidneys could potentially aid certain individuals in controlling their blood pressure.

A study led by researchers at Columbia University (New York, NY, USA) and Université de Paris (Paris, France) found that the device significantly lowered daytime ambulatory blood pressure by an average of 8.5 units in middle-aged individuals with hypertension. It is believed that hypertension in middle age is caused, in part, by overactive nerves in the kidneys that trigger water and sodium retention and release hormones, thereby raising blood pressure. Antihypertensive medications regulate blood pressure through different mechanisms, such as dilating blood vessels, removing excess fluid, or blocking hormones that increase blood pressure. However, none of these medications directly target the renal nerves. Ultrasound therapy reduces the overactivity of nerves in the renal artery and disrupts the signals that lead to hypertension. The treatment is administered to the nerves through a thin catheter inserted into a leg or wrist vein and threaded up to the kidney.

The latest research analyzed data from three randomized trials involving over 500 middle-aged patients who had varying degrees of hypertension and were treated with different medications. It was discovered that twice the number of patients who underwent ultrasound therapy achieved their targeted daytime blood pressure (less than 135/85 mmHg) compared to those in the control groups. The treatment was well-tolerated, and most patients were released from the hospital the same day. The researchers observed improvements in blood pressure just a month after the procedure. The treatment is anticipated to be reviewed by the FDA in the near future. The researchers believe that this treatment, when used with medication therapy and lifestyle changes, could be a valuable tool in controlling unmanageable hypertension.

“Renal ultrasound could be offered to patients who are unable to get their blood pressure under control after trying lifestyle changes and drug therapy, before these events occur,” said Ajay Kirtane, MD, professor of medicine at Columbia University Vagelos College of Physicians and Surgeons and co-leader of the study. “Once the device is available, we envision recommending it to patients who have tried other therapies first. The hope is that by controlling blood pressure, we might be able to prevent kidney damage and other effects of uncontrolled blood pressure.”

Related Links:
Columbia University
Université de Paris

Print article



view channel
Image: Physicians using the Zenition 90 Motorized mobile X-ray system (Photo courtesy of Royal Philips)

High-Powered Motorized Mobile C-Arm Delivers State-Of-The-Art Images for Challenging Procedures

During complex surgical procedures, clinicians depend on surgical imaging systems as they navigate challenging anatomy to quickly visualize small anatomical details while minimizing X-ray exposure.... Read more

Nuclear Medicine

view channel
Image: 68Ga-NC-BCH whole-body PET imaging rapidly targets an important gastrointestinal cancer biomarker in lesions in GI cancer patients (Photo courtesy of Qi, Guo, et al.; doi.org/10.2967/jnumed.123.267110)

New PET Radiotracer Enables Same-Day Imaging of Key Gastrointestinal Cancer Biomarker

Gastrointestinal cancers rank among the most prevalent cancers worldwide, contributing to over a quarter of all cancer cases and over one-third of cancer-related deaths annually. The initial symptoms of... Read more

General/Advanced Imaging

view channel
Image: The denoised image is less noisy and the defect is more detectable and visually clearer with DEMIST (Photo courtesy of Abhinav Jha/WUSTL)

Artificial Intelligence Tool Enhances Usability of Medical Images

Doctors use myocardial perfusion imaging (MPI) single-photon emission computed tomography (SPECT) images to evaluate blood flow to the heart muscle. To capture these images, patients are administered a... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.