We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Magnetic Particle Imaging Device Identifies Alzheimer's Risk before Symptoms Onset

By MedImaging International staff writers
Posted on 08 Sep 2023
Print article
Image: The magnetic particle imaging device is capable of producing images of the human brain (Photo courtesy of Mitsubishi Electric)
Image: The magnetic particle imaging device is capable of producing images of the human brain (Photo courtesy of Mitsubishi Electric)

The prevalence of dementia, particularly Alzheimer's disease, continues to rise globally. Medications targeting the accumulation of amyloid-β in the brain, a potential contributor to Alzheimer's, have shown promise in slowing disease progression. Early intervention during periods of low amyloid-β buildup in the brain can delay disease onset. Therefore, there exists a critical need for technology capable of measuring amyloid-β accumulation and distribution. Now, the world's first high-sensitivity imaging device designed to operate at low frequencies with a compact power supply could revolutionize pre-Alzheimer's diagnosis. This device can image magnetic particles that bind to amyloid-β, the causative agent of Alzheimer's, enabling quantitative assessment of amyloid-β accumulation and distribution. The goal is to enable imaging-based predictions of Alzheimer's risk before symptoms manifest in the patient.

A team of scientists at Mitsubishi Electric (Tokyo, Japan), Okayama University (Okayama, Japan) and Osaka University (Suita, Japan) have developed the world's first high-sensitivity imaging device that operates at frequencies of 1 kHz or less, significantly reducing the power supply unit's size. Higher-frequency alternating magnetic fields enhance signal detection sensitivity. Existing compact devices, suitable for small animal testing like mice, typically use frequencies of around 25 kHz. The main challenge in adapting this technology for human use was the bulky power supply unit required to drive a larger coil. The device employs an alternating magnetic field generated by a coil to induce magnetic signals from injected magnetic particles within the body, using these signals to generate a three-dimensional image.

Drawing on their extensive expertise in electromagnetic technology and optimizing coil configurations for generating alternating magnetic fields and signal detection, Mitsubishi Electric devised a method that minimizes unwanted signals (noise) that can interfere with magnetic signal detection. This has enabled the development of a magnetic particle imaging device capable of sensitively capturing magnetic particle images across an area equivalent to the human brain's size. Most importantly, its ability to operate at frequencies below 1 kHz is a pioneering achievement that dramatically reduces the size of the necessary power supply unit. This breakthrough represents a significant leap toward realizing imaging tests capable of assessing the risk of Alzheimer's development before symptoms emerge.

Related Links:
Mitsubishi Electric
Okayama University
Osaka University 

Gold Supplier
Ultrasound System
Gold Supplier
Conductive Gel
Silver Supplier
IMRT Thorax Phantom
CIRS Model 002LFC
Ultrasound System Drapes
Ultrasound System Drapes

Print article



view channel
Image: Intelligent NR provides high-quality diagnostic images containing significantly less grainy noise (Photo courtesy of Canon)

AI-Driven DR System Produces Higher Quality Images While Limiting Radiation Doses in Pediatric Patients

Ionizing radiation is a fundamental element in producing diagnostic X-rays, yet it's widely acknowledged for its cancer risk potential. Digital projection radiography, a vital imaging modality, accounts... Read more


view channel
Image: The researchers are using MRI-guided radiation therapy that pairs daily MRIs with radiation treatment (Photo courtesy of Sylvester)

AI Technique Automatically Traces Tumors in Large MRI Datasets to Guide Real-time Glioblastoma Treatment

Treating glioblastoma, a prevalent and aggressive brain cancer, involves the use of radiation therapy guided by CT imaging. While this method is effective in targeting radiation, it doesn't provide real-time... Read more


view channel
Image: The new ultrasound patch can measure how full the bladder is (Photo courtesy of MIT)

Ultrasound Patch Designed to Monitor Bladder and Kidney Health Could Enable Earlier Cancer Diagnosis

Bladder dysfunction and related health issues affect millions worldwide. Monitoring bladder volume is crucial for assessing kidney health. Traditionally, this requires a visit to a medical facility and... Read more

Nuclear Medicine

view channel
Image: A novel PET radiotracer facilitates early, noninvasive detection of IBD (Photo courtesy of Karmanos)

New PET Radiotracer Aids Early, Noninvasive Detection of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is an inflammatory condition of the gastrointestinal tract affecting roughly seven million individuals globally.... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more

Industry News

view channel
Image: Attendees can discover innovative products and technology in the RSNA 2023 Technical Exhibits (Photo courtesy of RSNA)

RSNA 2023 Technical Exhibits to Offer Innovations in AI, 3D Printing and More

The 109th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA, Oak Brook, IL, USA) to be held in Chicago, Nov. 26 to 30 is all set to offer a vast array of medical... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.