We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Molecular Imaging Technique Improves Endometriosis Diagnosis

By MedImaging International staff writers
Posted on 08 Jun 2022
Print article
Image: 99mTc-maraciclatide planar imaging has the capacity to image the whole body (Photo courtesy of Serac Healthcare)
Image: 99mTc-maraciclatide planar imaging has the capacity to image the whole body (Photo courtesy of Serac Healthcare)

Endometriosis is a common inflammatory condition affecting women, associated with painful periods, chronic pelvic pain, and infertility. It is believed to be due to tissue that resembles the lining of the womb sticking to areas outside the uterus, usually in the pelvis. However, diagnosing endometriosis often results in multiple visits to physicians, multiple scans and often surgery to confirm the diagnosis. As a result, there is a delay to get a diagnosis of endometriosis, mainly due to lack of non-invasive tests capable of detecting all endometriosis subtypes (ovarian, superficial, and deep disease). Now, a new research study is investigating whether a 20-minute imaging scan can detect the most common types of endometriosis, which currently require surgery to diagnose.

Endometriosis experts at the University of Oxford (Oxford, UK) have joined hands with Serac Healthcare Ltd. (London, UK) to investigate whether an experimental imaging marker (⁹⁹ᵐTc maraciclatide) that binds to areas of inflammation can be used in endometriosis to visualize the disease on a scan. The imaging marker has been used for detecting inflammation in conditions such as rheumatoid arthritis in other research studies across the UK, EU and US. Maraciclatide is for investigational use only and is not approved by the FDA or UK and European regulatory authorities.

The potential strengths of the scan lie in the way the imaging marker binds to areas of inflammation, which may allow doctors to distinguish between new and old lesions and detect endometriosis in areas not easily seen during surgery such as the lung. The development of a 20-minute imaging test would reduce the need for repeated visits to doctors, for repeated investigations, and for invasive surgery to obtain a diagnosis. This would ultimately reduce the time taken to confirm or exclude endometriosis.

Initially, the study will involve women who are scheduled to have planned surgery for suspected endometriosis. Two to seven days before their operation, the participants will be invited for an imaging scan which will compare the suspected locations of disease detected on the scan and in surgery to confirm whether this imaging test could be an effective non-invasive method of detecting all endometriosis subtypes.

“There is an urgent unmet clinical need for a non-invasive marker to identify or rule out endometriosis as it is such a very common disease affecting more than 190 million women worldwide,” said Professor Christian Becker, Co-Director of the Endometriosis CaRe Centre in Oxford, who will lead the study.

“We are excited about the potential of ⁹⁹ᵐTc maraciclatide to diagnose endometriosis non-invasively and delighted to be working with the internationally renowned team at Oxford on this important first study,” said David Hail, CEO of Serac Healthcare.

Related Links:
University of Oxford 
Serac Healthcare Ltd. 


Print article
Radcal
CIRS -  MIRION

Channels

Radiography

view channel
Image: Spinal fractures in the elderly are preventable with simple X-rays (Photo courtesy of Pexels)

Simple X-Ray Method Can Diagnose Vertebral Compression and Prevent Spinal Fractures

Vertebral compression means that the spine is compressed, causing a fracture in one of the vertebrae. Vertebral compression fractures (VCFs) occur easily in people with osteoporosis and are very common... Read more

Imaging IT

view channel
Illustration

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more

Industry News

view channel
Image: RSNA`s annual meeting is the world`s largest medical imaging conference (Photo courtesy of RSNA)

RSNA 2022 Sees Rise in Abstract Submissions Ahead of Annual Meeting

The Radiological Society of North America (RSNA, Oak Brook, IL, USA) has announced that nearly 10,400 scientific and educational abstracts have been submitted for the Society's 108th Scientific Assembly... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.