We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Radioembolization Microspheres Treat Hepatocellular Carcinoma

By MedImaging International staff writers
Posted on 29 Mar 2021
Print article
Image: A vial of TheraSphere contains millions of microscopic glass beads containing yttrium (Photo courtesy of Boston Scientific)
Image: A vial of TheraSphere contains millions of microscopic glass beads containing yttrium (Photo courtesy of Boston Scientific)
A selective internal radiation therapy (SIRT) platform delivers radioactive glass microspheres directly to liver tumors, with minimal exposure to surrounding healthy tissue.

Boston Scientific (Natick, MA, USA) TheraSphere treatment is a low toxicity SIRT comprised of millions of microscopic glass beads containing yttrium (Y-90) that are delivered to a Hepatocellular Carcinoma (HCC) through a catheter placed into the hepatic artery, which provides the main blood supply to the HCC. The microspheres, which are unable to traverse the tumor vasculature, are embolized within the tumor, exerting a local beta radiation radiotherapeutic effect, as the average range of the radiation in tissue is 2.5 mm, with a maximum range less than one centimeter.

TheraSphere is available in three dose sizes, each supplied with an administration set consisting of a single use, pre-assembled vial with inlet and outlet lines that facilitate infusion of the microspheres to the catheter. Each milligram of TheraSphere contains between 22,000 and 73,000 microspheres of Y-90. The treatment does not require hospitalization, and is typically performed as an outpatient procedure in as little as an hour. TheraSphere has been approved by the FDA after almost 20 years of humanitarian exemption device (HDE).

“The FDA approval will expand access to TheraSphere, which has demonstrated improvement in both survivability and quality of life through 20 years of clinical trials and real-world outcomes in the more than 70,000 patients globally,” said Peter Pattison, president of interventional oncology and peripheral interventions at Boston Scientific. “We expect to continue to focus our efforts on bringing this treatment to more patients, as well as further investigating the therapy for different cancer segments, including prostate and brain.”

As healthy liver tissue is mainly perfused by the portal vein, and most liver malignancies derive their blood supply from the hepatic artery, trans-arterial radioembolization (TARE) using radioactive Yttrium radioactive glass microspheres can be selectively administered to the tumors. The microspheres lodge in the small vessels of the tumor (embolization), emitting localized RT to targeted segments, results in tissue necrosis. The Y-90, with a half-life of 3.85 days, decays to Zirconium-90.

Related Links:
Boston Scientific

Gold Supplier
Portable X-Ray System
FDR Xair
New
Retrofittable DR Mammography Solution
AirDR M
New
Full-Body Fan-Beam System
Primus DXA
New
Flat Panel Detector (FPD)
DRX-LC Detector

Print article
Sun Nuclear -    Mirion
FIME - Informa

Channels

Radiography

view channel
Image: BiOI ruby-like crystals can improve medical imaging safety by lowering intensities of harmful X-rays (Photo courtesy of University of Cambridge)

Sustainable Solar Cell Material Could Revolutionize Medical Imaging

The use of X-rays for internal body imaging has dramatically changed non-invasive medical diagnostics. Yet, the high dose of X-rays required for these imaging techniques, due to the poor performance of... Read more

MRI

view channel
Image: An international, multi-institutional project aims to develop a radically new MRI scanner that is compact and transportable (Photo courtesy of U of M Medical School)

Compact and Portable MRI Scanner to Expand Existing Imaging Capabilities and Accessibility

Magnetic Resonance Imaging (MRI) technology which provides detailed images of the human brain is instrumental in understanding brain functions and diagnosing medical conditions. MRI has become indispensable... Read more

Ultrasound

view channel
Image: A new study has shown the value of endoscopic ultrasound in NSCLC (Photo courtesy of Freepik)

Endoscopic Ultrasound Can Provide Value in NSCLC, Finds Study

The usefulness of confirmatory mediastinoscopy following tumor-negative results on endoscopic ultrasound still remains debatable among researchers. This procedure is often employed for mediastinal staging... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more

Industry News

view channel
Image: The global AI-enabled medical imaging solutions market is expected to reach USD 18.36 billion in 2032 (Photo courtesy of Freepik)

Global AI-Enabled Medical Imaging Solutions Market Driven by Need for Early Disease Detection

The AI-enabled medical imaging solutions market is currently in its developmental stages, following the significant role of AI-based tools in combating the COVID-19 pandemic. The pandemic saw an upswing... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.