We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Thales AVS France

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Prostate Cancer Survivors Can Forgo Postoperative Radiotherapy

By MedImaging International staff writers
Posted on 08 Oct 2019
Print article
A new study shows no difference in disease recurrence between men who underwent radiotherapy (RT) shortly after surgery and men who had RT later.

Researchers at University College London (UCL, United Kingdom), The Royal Marsden NHS Foundation Trust (London, United Kingdom), the Institute of Cancer Research (ICR; London, United Kingdom), and other institutions conducted a study that enrolled 1,396 patients after surgery for prostate cancer from the UK, Denmark, Canada, and Ireland. The men were randomly allocated to postoperative RT or the standard approach of observation only, with RT kept as an option if the disease recurred.

The results showed that at a median follow-up of five years, progression free survival was 85% in the postoperative RT group and 88% in the standard care group. Self-reported urinary incontinence was worse at one year in 5.3% of patients receiving RT, compared to 2.7% who had standard care. Radiation Therapy Oncology Group (RTOG) grade 3/4 urethral stricture was reported at any time in 8% versus 5% of the RT and standard care groups, respectively. The study was presented at the European Society for Medical Oncology (ESMO) annual meeting, held during September 2019 in Barcelona (Spain).

“The results suggest that radiotherapy is equally effective whether it is given to all men shortly after surgery or given later to those men with recurrent disease,” said lead author and study presenter Professor Chris Parker, MD, of The Royal Marsden NHS Foundation Trust and the ICR. “The good news is that in future, many men will avoid the side effects of radiotherapy. These include urinary leakage and narrowing of the urethra, which can make urination difficult. Both are potential complications after surgery alone, but the risk is increased if radiotherapy is used as well.”

Adjuvant RT, directed to where the resected prostate was located in the pelvis, is intended to kill any lingering prostate cancer cells left behind, and improve the chance of cure. On the other hand, it may cause problems with bladder, bowel, or sexual function. In some men it may be futile if the prostate cancer cells have already spread beyond the pelvis.

Related Links:
University College London
The Royal Marsden NHS Foundation Trust
Institute of Cancer Research


Print article
CIRS
Sun Nuclear

Channels

Imaging IT

view channel
Illustration

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more

Industry News

view channel
Image: GE Healthcare to be Spun Off in 2023 to Create Pure-Play Company at Center of Precision Health (Photo courtesy of GE Healthcare)

GE Healthcare to be Spun Off in 2023 to Create Pure-Play Company at Center of Precision Health

General Electric (GE; Boston, MA, USA) plans to pursue a tax-free spin-off of GE Healthcare, creating a pure-play company at the center of precision health in early 2023. The spin-off of GE Healthcare... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.