We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Radiotherapy Doubles Mesothelioma Survival Rate

By MedImaging International staff writers
Posted on 15 May 2019
Print article
Mesothelioma patients treated with a high dose of radiation to the affected side of the trunk are twice as likely to survive for two years or longer, according to a new study.

Researchers at University Hospital of Udine (Italy) and the National Cancer Institute (CRO; Aviano, Italy) conducted a study that involved 108 patients with malignant pleural mesothelioma treated between 2014 and 2018 at the CRO. Half of the patients were randomly assigned to receive radical hemi-thoracic radiotherapy (RT) involving a total of 25 treatments, delivering a total dose of 50 Gy to the left or right side of the trunk, as well as an extra 60 Gy dose to the precise location of the tumor.

The other half of the patients received a more typical palliative form of RT, which involved five to ten treatments delivering a total dose of 20-30 Gy to the precise tumor location. All patients also received subsequent chemotherapy. The results showed that of the patients who received aggressive RT, 58% were still alive two years later, compared to 28% in the palliative RT group. Treatment side effects included radiation pneumonitis, weakness, nausea, and mild inflammation of the esophagus. The study was presented at the ESTRO 38 annual conference, held during April 2019 in Milan (Italy).

“There is an urgent need for more effective treatments for mesothelioma. Surgery can be given to these patients, but it is often impossible to remove all of the tumor,” said lead author Marco Trovo MD, chief of the radiation oncology department. “This research shows a clear survival benefit in using this type of radiotherapy for mesothelioma patients whose tumors can only partially be removed by surgery. We believe that this should be considered the new standard of care for these patients.”

Mesothelioma develops from the mesothelium lining that covers many of the internal organs; the most common area affected is the lining of the lungs and chest wall. Signs and symptoms include shortness of breath due to fluid around the lung, a swollen abdomen, chest wall pain, cough, exhaustion, and weight loss. More than 80% of mesothelioma cases are caused by exposure to asbestos, with exposure and the onset of cancer generally separated by about 40 years. Mesothelioma is generally resistant to radiation and chemotherapy treatment, and long-term survival and cures are exceedingly rare.

Related Links:
University Hospital of Udine
National Cancer Institute

Gold Supplier
SBRT Phantom with Removable Spine
E2E SBRT Phantom with Removable Spine Model 036S-CVXX-xx
Data Management Platform
Ultrasound System
MyLab X1
Air Displacement Plethysmography System

Print article



view channel
Image: MRI scan showing the fetus and placental compartments (Photo courtesy of WUSTL)

New MRI Method Automatically Detects Placental Health during Pregnancy

Early monitoring of the placenta can improve detection and prevention of pregnancy complications, such as preterm birth, fetal growth disorders and preeclampsia. Currently, standard MRI analysis methods... Read more


view channel
Image: The new Clarius MSK AI model speeds up diagnosis and treatment of musculoskeletal injuries (Photo courtesy of Clarius)

Handheld MSK Ultrasound Scanner Uses AI to Automatically Identify and Measure Tendons in Foot, Ankle and Knee

An artificial intelligence (AI) application for musculoskeletal (MSK) imaging that works with handheld point-of-care ultrasound devices automatically identifies, highlights, and measures tendon structures... Read more

General/Advanced Imaging

view channel
Image: CZT gamma detector for SPECT imaging (Photo courtesy of Kromek)

Low-Dose Molecular Breast Imaging (MBI) Could Improve Cancer Detection in Dense Breast Tissue

Traditional mammography is often less able to clearly image tumors due to the density of the breast tissue. Molecular breast imaging (MBI) technology uses a radioactive tracer that ‘lights up’ areas of... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.