We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Groundbreaking MRI Technology Distinguishes Between Pathological and Healthy Brain Tissue without Using Contrast Agents

By MedImaging International staff writers
Posted on 13 Sep 2023
Print article
Image: The new MRI technology assesses normal and impaired iron homeostasis in the brain (Photo courtesy of 123RF)
Image: The new MRI technology assesses normal and impaired iron homeostasis in the brain (Photo courtesy of 123RF)

Conventional magnetic resonance imaging (MRI) offers images that require healthcare experts to interpret them based on their experience and understanding. On the other hand, quantitative MRI aims for the level of accuracy one can expect from taking someone's temperature when they're sick—going beyond general terms like "too warm" or "too cold." To do this, complex physical models are used to combine data from various MRI scans to obtain a wide range of measurements. Just like a blood test gives detailed information about the substances in the blood, these MRI measurements provide critical biological insights. One such vital insight is about iron balance in the brain, which is essential for overall health. Issues with this balance could indicate problems like degenerative brain conditions and even cancer. However, until recently, non-invasive methods to study the iron environment in the living human brain were lacking.

Now, a research team led by The Hebrew University of Jerusalem (Jerusalem, Israel) has introduced a revolutionary MRI technology that could revolutionize the understanding of iron homeostasis in the brain. This advanced technique enables the non-invasive examination of various molecular iron environments within the human brain, providing insights into its role in regular brain activities, aging, and diseases like neurodegeneration and cancer. Built on quantitative MRI, this new approach is sensitive enough to pick up changes in the brain's iron balance. During lab experiments, the technology could distinguish the unique magnetic properties of essential iron compounds, such as ferritin, transferrin, and ferrous iron. Moreover, real-world tests on patients with brain tumors validated the technology's effectiveness.

What sets this new MRI approach apart is its ability to notice shifts in the brain's capacity to manage iron, both across various regions and as the brain ages. The technology can also identify changes in how iron is handled and how genes related to iron are expressed in abnormal tissues. Perhaps most significantly, it can differentiate between cancerous and non-cancerous tissues without needing potentially harmful contrast agents. This new approach to MRI marks a groundbreaking advancement in assessing iron balance in the human brain. It not only avoids the use of toxic agents but also provides data that conventional MRIs are unable to capture. The technology holds great promise for advancing knowledge about disorders related to iron levels and offers new paths for both research and diagnosis in live human brains.

"Our technology opens up new possibilities for understanding the role of iron in cancer, normal aging, and neurodegenerative diseases,” said Shir Filo from the Hebrew University of Jerusalem. “It enables non-invasive research and diagnosis of iron homeostasis in the living human brain, offering a potential game-changer for healthcare and neuroscience.”

Related Links:
The Hebrew University of Jerusalem 

Gold Supplier
Conductive Gel
Gold Supplier
128 Slice CT Scanner
Supria 128
Diagnostic Ultrasound System
DRE Crystal 4P
Lead Apron
Standard Regular Vest

Print article
Sun Nuclear -    Mirion



view channel
Image: The AI model improves tumor removal accuracy during breast cancer surgery (Photo courtesy of UNC School of Medicine)

AI Model Analyzes Tumors Removed Surgically in Real-Time

During breast cancer surgery, the surgeon removes the tumor, also known as a specimen, along with a bit of the adjacent healthy tissue to ensure all cancerous cells are excised. This specimen is then X-rayed... Read more


view channel
Image: FloPatch is a revolutionary tool that facilitates real-time precision in IV fluid management in sepsis (Photo courtesy of Flosonics)

Wireless, Wearable Doppler Ultrasound Revolutionizes Precision Fluid Management in Sepsis Care

When a patient comes to the hospital with sepsis, administering intravenous (IV) fluids is usually the first course of action. However, too much IV fluid can do more harm than good, causing additional... Read more

Nuclear Medicine

view channel
Image: An AI model can evaluate brain tumors on PET (Photo courtesy of Freepik)

AI Model for PET Imaging Determines Patient Response to Brain Tumor Treatments

The assessment of changes in metabolic tumor volume (MTV) through PET scans using specific radiotracers like F-18 fluoroethyl tyrosine (FET) plays a vital role in evaluating the treatment response in patients... Read more

General/Advanced Imaging

view channel
Image: Annalise Enterprise CTB acts like a ‘second pair of eyes’ for radiologists (Photo courtesy of Annalise.ai)

Deep Learning System Boosts Radiologist Accuracy and Speed for Head CTs

Non-contrast computed tomography of the brain (NCCTB) is a commonly employed method for identifying intracranial pathology. Despite its frequent use, the complex scan outcomes are prone to being misunderstood.... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.