We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
02 Oct 2021 - 06 Oct 2021
Virtual Venue

Early MRI Helps Identify Takotsubo Cardiomyopathy

By MedImaging International staff writers
Posted on 13 May 2021
Print article
Image: Early CMR can help identify broken hearts (Photo courtesy of Getty Images)
Image: Early CMR can help identify broken hearts (Photo courtesy of Getty Images)
A new study suggests that early cardiovascular magnetic resonance (CMR) imaging of the heart can greatly increase broken-heart syndrome diagnosis rates.

Researchers at Karolinska Institutet (Solna, Sweden), the Kolling Institute (Sydney, Australia), Karolinska University Hospital (Stockholm, Sweden), and other institutions conducted a prospective study involving 148 patients with myocardial infarction with non-obstructed coronary arteries (MINOCA) in order to determine if 1.5-T CMR imaging with T1 and extracellular volume mapping early after hospital admission could aid diagnosis; 150 patients with MINOCA imaged using 1.5-T CMR without mapping techniques served as historic controls.

The results showed that 77% of the patients imaged together with extracellular volume mapping could be given a diagnosis (35% of Takotsubo syndrome and 17% of myocardial inflammation), compared with 19% and 7% (respectively), in those imaged without mapping techniques. The early CMR imaging with extracellular volume mapping also detected significantly more wall motion abnormalities, edema, and late gadolinium enhancement, compared to those examined without mapping techniques. The study was published on April, 14, 2021, in JACC Cardiovascular Imaging.

“Around eighty to ninety per cent of broken-heart sufferers are women, and the disease is associated with mental stress,” said senior author Professor Per Tornvall, MD, PhD, of Karolinska Institutet. “There also seems to be a link to hypersensitivity towards stress caused by low oestrogen levels. Unfortunately, research on the investigation and treatment of myocardial infarction is often done on men, while female heart disease is less studied.”

Takotsubo syndrome occurs in response to physical or emotional distress and causes dysfunction or failure in the heart muscle. Patients typically experience symptoms similar to a heart attack, such as chest pain and shortness of breath, but usually do not have acutely blocked coronary arteries. The left ventricle of the heart, however, may show enlargement. Other symptoms include irregular heartbeat, fainting, low blood pressure, and cardiogenic shock. Patients generally recover in a matter of days or weeks, although the condition can occasionally cause major adverse cardiac and cerebrovascular events, and rarely can be fatal.

Related Links:
Karolinska Institutet
Kolling Institute
Karolinska University Hospital

Print article


Industry News

view channel

Fujifilm Introduces AI-Powered Chest X-Ray Software in Collaboration with Lunit

Fujifilm Corporation (Tokyo, Japan) has announced that its software for analyzing chest X-ray developed with the core artificial intelligence (AI) technology of Lunit (Seoul, Korea) will be commercially... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.