MR Imaging, Motor Score Modeling Predicts Recovery After Spinal Cord Injury

For people suffering with spinal cord injuries (SCIs), the time following the injury are filled with uncertainty about their potential for recovery and future independence. A new model based on motor scores at admission and early imaging studies may allow clinicians to predict functional outcomes and guide decision-making for therapy and care-giving needs.

These new findings were published August 10, 2012, in the Journal of Neurotrauma. The innovative prediction model, which combines acute functional measures and evidence of injury on magnetic resonance imaging (MRI) including swelling and bleeding around the spinal cord, and which was gathered from two large clinical datasets, could help guide treatment decisions, classification of patents for clinical trials, and counseling of patients and families.

Jefferson Wilson, MD, Michael Fehlings, MD, PhD, from University of Toronto (Canada) and Toronto Western Hospital (Canada), and colleagues from the US described the prediction model and its potential applications. “An important goal of medical research is to identify early surrogate markers that could assist treating physicians in determining appropriate therapeutic strategies,” said W. Dalton Dietrich, III, PhD, The Miami Project to Cure Paralysis, University of Miami (FL, USA) and deputy editor of the journal. “This article provides important information that could help predict the potential for recovery after SCI and thereby direct treatment options.”

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