MR Technique Detects Condition in Women That Often Goes Undiagnosed

In women with lower urinary tract symptoms an imaging technique called dynamic magnetic resonance imaging (dMRI) allows clinicians to diagnose pelvic organ prolapse--a condition that frequently goes undiagnosed on static MRI and at physical examination.

Pelvic organ prolapse is comparatively common and occurs when the pelvic floor muscles become weak or damaged and can no longer support the pelvic organs. If left untreated, living with prolapse can be a challenge, both physically and emotionally, as the symptoms can disrupt day-to-day life. Dynamic MRI is performed while the patient performs a straining maneuver, such as bearing down. Static MRI is performed while the patient is at rest.

The study performed at New York University (NYU) Langone Medical Center (New York, NY, USA), included 84 women with lower urinary tract symptoms who underwent dynamic and static MRI scans for a suspected urethra abnormality. Ten of the 84 patients were found to have an abnormality of the urethra.

"However 33 patients were diagnosed with pelvic organ prolapse, of whom 29 were diagnosed exclusively on dynamic imaging,” said Genevieve L. Bennett, M.D., assistant professor of radiology at NYU Langone Medical Center and lead author of the study. "Dynamic imaging allows for the detection of pelvic organ prolapse, which may not be evident at rest but only detected when the woman strains. The results of our study show that in women with lower urinary tract symptoms who undergo MRI for evaluation of a suspected urethra abnormality, the addition of dMRI permits detection of pelvic organ prolapse that may not be evident on static at rest images and that may also go undetected at physical examination,” she said.

This study appears in the December 2009 issue of the American Journal of Roentgenology (AJR).

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New York University Langone Medical Center