We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
30 Jan 2023 - 02 Feb 2023

Ultrasound Combined With Nanobubbles Enables Removal of Tumors Without Surgery

By MedImaging International staff writers
Posted on 23 Nov 2022
Print article
Image: A combination of ultrasound and nanobubbles allows cancerous tumors to be destroyed without surgery (Photo courtesy of Tel Aviv University)
Image: A combination of ultrasound and nanobubbles allows cancerous tumors to be destroyed without surgery (Photo courtesy of Tel Aviv University)

The prevalent method of cancer treatment is surgical removal of the tumor, in combination with complementary treatments such as chemotherapy and immunotherapy. Therapeutic ultrasound to destroy the cancerous tumor is a non-invasive alternative to surgery. This method has both advantages and disadvantages. On the one hand, it allows for localized and focused treatment; the use of high-intensity ultrasound can produce thermal or mechanical effects by delivering powerful acoustic energy to a focal point with high spatial-temporal precision. This method has been used to effectively treat solid tumors deep within in the body. Moreover, it makes it possible to treat patients who are unfit for tumor resection surgery. The disadvantage, however, is that the heat and high intensity of the ultrasound waves may damage the tissues near the tumor.

Now, a new technology developed at Tel Aviv University (Tel Aviv, Israel) makes it possible to destroy cancerous tumors in a targeted manner, via a combination of ultrasound and the injection of nanobubbles into the bloodstream. According to the research team, unlike invasive treatment methods or the injection of microbubbles into the tumor itself, this latest technology enables the destruction of the tumor in a non-invasive manner.

In their study carried out using an animal model, the researchers were able to destroy the tumor by injecting nanobubbles into the bloodstream (as opposed to what has been until now, which is the local injection of microbubbles into the tumor itself), in combination with low-frequency ultrasound waves, with minimal off-target effects. The nanobubbles and ultrasound waves cause the bubbles concentrated in the cancerous tumor to explode. The treatment was performed using safe, low-pressure levels and focused only on the area of tumor, which reduces off-target toxicity and avoids damage to healthy tissues. The use of low-frequency ultrasound also increases the depth of penetration, minimizes distortion and attenuation, and enlarges the focal point.

“Our new technology makes it possible, in a relatively simple way, to inject nanobubbles into the bloodstream, which then congregate in the area of ​​the cancerous tumor. After that, using a low-frequency ultrasound, we explode the nanobubbles, and thereby the tumor,” said Dr. Tali Ilovitsh at Tel Aviv University’s Department of Biomedical Engineering who led the research. “The combination of nanobubbles and low frequency ultrasound waves provides a more specific targeting of the area of the tumor, and reduces off-target toxicity. Applying the low frequency to the nanobubbles causes their extreme swelling and explosion, even at low pressures. This makes it possible to perform the mechanical destruction of the tumors at low-pressure thresholds. Our method has the advantages of ultrasound, in that it is safe, cost-effective, and clinically available, and in addition, the use of nanobubbles facilitates the targeting of tumors because they can be observed with the help of ultrasound imaging.”

Related Links:
Tel Aviv University

New
Gold Supplier
Premium Ultrasound Scanner
ARIETTA 850
New
POC Ultrasound System
Acclarix AX3
New
Digital Radiographic System
Vieworks VIVIX-S
New
Handheld Ultrasound Machine
SonoEye P3

Print article
CIRS -  MIRION

Channels

Radiography

view channel
Researchers used AI to triage patients with chest pain (Photo courtesy of Pexels)

First Deep Learning AI Model Triages Patients with Chest Pain Using X-Rays

Acute chest pain syndrome can involve tightness, burning or other discomfort in the chest or a severe pain that spreads to the back, neck, shoulders, arms, or jaw, accompanied by shortness of breath.... Read more

Nuclear Medicine

view channel
Image: Tracking radiation treatment in real time promises safer, more effective cancer therapy (Photo courtesy of Pexels)

Real-Time 3D Imaging Provides First-of-Its-Kind View of X-Rays Hitting Inside Body During Radiation Therapy

Radiation is used in treatment for hundreds of thousands of cancer patients each year, bombarding an area of the body with high energy waves and particles, usually X-rays. The radiation can kill cancer... Read more

General/Advanced Imaging

view channel
Image: The HIAS-29000 brain PET scanner with motion correction (Photo courtesy of Hamamatsu Photonics)

New Brain PET Scanner Corrects Blurring in Images Caused by Body Motion

Ordinary brain PET (positron emission tomography) scanners are unable to accurately measure the distribution of radiopharmaceuticals in the brain if the patients move their head during the examination process.... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.