We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
30 Jan 2023 - 02 Feb 2023

AI Tool Uses CT Scans to Identify Patients at Risk of Reduced Blood Flow to the Heart

By MedImaging International staff writers
Posted on 22 Nov 2022
Print article
Image: AI tool predicts reduced blood flow to the heart (Photo courtesy of Pexels)
Image: AI tool predicts reduced blood flow to the heart (Photo courtesy of Pexels)

Blockages of the coronary arteries typically occur due to the buildup of fatty plaques. This may restrict blood flow to the heart, causing chest pain, heart attacks, or even death. Identifying which arteries are at risk for reduced blood flow can help inform doctors as to which patients should be referred for subsequent tests or placement of stents. The current clinical standard for diagnosing reduced coronary arterial blood flow is called invasive fractional flow reserve (FFR). It measures the drop in pressure within the arteries and thus calculates how much each blockage limits blood flow. Meanwhile, a heart positron emission tomography (PET) scan is an imaging test that uses a radioactive tracer to look for reduced blood flow in the heart muscle.

Now, investigators at Cedars-Sinai (Los Angeles, CA, USA) and their colleagues have developed an artificial intelligence (AI) tool that uses computed tomography (CT) scans to identify patients at risk of reduced blood flow to the heart. The tool is able to accurately predict reduced blood flow both within the coronary arteries and the heart muscle. The advantage of this AI tool is that it could potentially be used in real time during routine patient visits for CT scans to help doctors determine the next step in the treatment plan.

The investigators analyzed data from 203 patients who had taken part in a previous study called the PACIFIC trial. As part of the PACIFIC trial, all patients had undergone multiple tests within a two-week interval, including coronary CT scans, invasive coronary angiography with FFR, and heart PET scans. The researchers developed an AI tool that analyzes features of the plaques on coronary CT scans, and then predicts the probability of reduced blood flow on invasive FFR and PET scans. This AI tool can be incorporated into routine analysis of coronary CT scans, according to the authors. Having this information on hand during patient visits could help doctors know which patients to refer for further testing, such as noninvasive stress testing or invasive coronary angiography. For some patients, this would mean avoiding invasive tests.

“Coronary CT angiogram is the first-line test for chest pain, as it allows us to measure the atherosclerotic plaque and narrowing,” said Damini Dey, PhD, director of the quantitative image analysis lab in the Biomedical Imaging Research Institute and professor of Biomedical Sciences and Medicine at Cedars-Sinai and corresponding author of the study. “If we can integrate CTA plaque data with stenosis with AI to predict impaired FFR, we could risk stratify patients correctly to realize the functional significance of the stenosis.”

Related Links:
Cedars-Sinai


Print article
Radcal
CIRS -  MIRION

Channels

MRI

view channel
Image: Hyperpolarized MRI technology reveals changes in heart muscle’s sugar metabolism after heart attack (Photo courtesy of ETH Zurich)

MRI Technology to Visualize Metabolic Processes in Real Time Could Improve Heart Disease Diagnosis

Magnetic resonance imaging (MRI) has become an indispensable part of medicine. It allows unique insights into the body and diagnosis of various diseases. However, current MRI technology has its limitations:... Read more

Ultrasound

view channel
Image: A combination of ultrasound and nanobubbles allows cancerous tumors to be destroyed without surgery (Photo courtesy of Tel Aviv University)

Ultrasound Combined With Nanobubbles Enables Removal of Tumors Without Surgery

The prevalent method of cancer treatment is surgical removal of the tumor, in combination with complementary treatments such as chemotherapy and immunotherapy. Therapeutic ultrasound to destroy the cancerous... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.