We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
15 Nov 2021 - 18 Nov 2021

Hexachromatic Camera Visualizes Cancer Cells During Surgery

By MedImaging International staff writers
Posted on 29 Jun 2021
Print article
Image: Mantis shrimp can perceive a wider range of colors than humans (Photo courtesy of UIL)
Image: Mantis shrimp can perceive a wider range of colors than humans (Photo courtesy of UIL)
A new intrasurgical camera inspired by the eyes of the Mantis shrimp provides further insights during cancer tumor surgery.

Developed at the University of Illinois (UIL; Urbana-Champaign, USA), Ss. Cyril and Methodius University (UKIM; Skopje, Republic of North Macedonia), and other institutions, the new camera replicates the Mantis shrimp’s visual system by providing a six-channel single-chip, combined color/near-infrared (NIR) image sensor that integrates arrays of vertically stacked silicon photodetectors and pixelated spectral filters to enable fluorescence image guidance during surgery, permitting an intuitive perspective of the surgical procedure.

The image sensor enabled simultaneous detection of two tumor-targeted fluorophores in athemic mice, distinguishing diseased from healthy tissue in 92% of cases. It also permitted extraction of NIR structured illumination, enabling the topographical mapping of tumors and surgical sites to within 1.2 mm error. In the operating room, during surgical resection in 18 patients with breast cancer, the sensor enabled sentinel lymph node mapping using clinically approved NIR fluorophores. The study was published on May 5, 2021, in Science Translational Medicine.

“The mantis shrimp has these incredible eyes. Humans perceive three colors – red, green, and blue – because of a single layer of light-sensitive cone cells that line our retina, but the mantis shrimp perceives upward of 12 colors thanks to the stacks of light-sensitive cells at the tip of its eye,” said lead author Steven Blair, MSc, an electrical and computer engineering graduate student at UIL. “The mantis shrimp’s little eyes can thus see things that humans can’t imagine – and do so in a fraction of the space.”

“The combination of this bioinspired camera and emerging tumor-targeted drugs will ensure that surgeons leave no cancer cells behind in the patient’s body,” said Professor Goran Kondov, MD, of UKIM, who demonstrated the technology in the operating room. “This additional set of eyes will help prevent recurrence of the disease, providing patients a quicker and easier path to recovery. And the device can potentially be manufactured at low cost since it is so simple, making it accessible to hospitals around the world. “

Many insects have a pair of compound eyes, such as dragonflies, bees, fruit-flies, grasshoppers, and mantis shrimp, among others. The compound eye of these insects, which is a sophisticated imaging device that consists of a mosaic of tiny optical units called ommatidia, allows them to see a different world from humans. For example, the compound eyes of bees can see ultraviolet (UV) light, making it easier to distinguish whether flowers are rich in nectar. The compound eyes of Mantis shrimp can not only detect multispectral information, but also recognize polarized light.

Related Links:
University of Illinois
Ss. Cyril and Methodius University



Print article
CIRS
Radcal

Channels

Ultrasound

view channel
Image: Mindray TE7 Max Ultrasound System (Photo courtesy of Mindray)

Mindray's New TE7 Max Ultrasound System Expands Possibilities for Point of Care

Mindray North America (Mahwah, NJ, USA) has launched its new TE7 Max ultrasound system that maximizes the potential of ultrasound in the Point of Care (POC) market. The TE7 Max has a 21.... Read more

Imaging IT

view channel
Illustration

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more

Industry News

view channel
Illustration

Intelerad Acquires Cloud Specialist Ambra Health to Form Global Enterprise Imaging Giant

Intelerad Medical Systems (Raleigh, NC, USA), a leading provider of medical image management solutions, has acquired Ambra Health (New York, NY, USA), maker of a leading cloud-based medical image management... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.