We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Bio-Inspired Imager Improves Cancer Surgery

By MedImaging International staff writers
Posted on 16 Apr 2018
Print article
A new camera that mimics the intricate visual system of a butterfly can improve sensitivity in near-infrared (NIR) fluorescence image-guided surgery, claims a new study.

Developed at the University of Illinois (UI; Urbana-Champaign, USA) and Washington University in St. Louis (WUSTL; MO, USA), the new camera is comprised of an artificial multispectral sensor--inspired by the Morpho butterfly’s compound eye--that interlaces nano-scale spectral tapetal filters with a photodetector array, thus enabling collection of color and NIR fluorescence information on one imaging device. The single-chip multispectral imager is 1,000 times more sensitive and offers seven times better spatial co-registration accuracy than current clinical imaging systems.

The unique design allows each pixel to take in the number of photons needed to build up an image; by changing exposure time so as to allow each pixel to detect the photons necessary, bright fluorescence images can be created without overexposing the color image of the tissue. Testing showed the camera seamlessly integrates into the surgical workflow, providing real-time information on cancerous tissue and sentinel lymph nodes. Integrating the detector array and optics into a single sensor makes it small, inexpensive, and insensitive to temperature changes. The study was published in the April 2018 issue of Optica.

“We realized that the problems of today's infrared imagers could be mitigated by using nanostructures similar to those in the Morpho butterfly. Their compound eyes contain photoreceptors located next to each other such that each photoreceptor senses different wavelengths of light in a way that is intrinsically co-registered,” said lead author Missael Garcia, PhD, of UI. “The bioinspired imager would be useful for removing various types of cancers, including melanomas, prostate cancer, and head and neck cancers.”

"During surgery, it is imperative that all the cancerous tissue is removed, and we've created an imaging platform that could help surgeons do this in any hospital around the world because it is small, compact and inexpensive,” said senior author Professor Viktor Gruev, PhD. “Under bright surgical lights, our instrument was 1,000 times more sensitive to fluorescence than the imagers currently approved. Because the bioinspired imager can reveal fluorescence that is deep in the tissue, it sped up the process of lymph node identification and helped surgeons find lymph nodes that couldn't be seen by eyesight alone.”

Image-guided surgery can enhance cancer treatment by decreasing, and ideally eliminating, positive tumor margins and iatrogenic damage to healthy tissue. Current state-of-the-art NIR fluorescence-imaging systems are bulky and costly, lack sensitivity under surgical illumination, and lack co-registration accuracy between multimodal images. As a result, an overwhelming majority of physicians still rely on unaided vision and palpation as primary sensing modalities for distinguishing cancerous from healthy tissue.

Related Links:
University of Illinois
Washington University in St. Louis

Gold Member
Solid State Kv/Dose Multi-Sensor
Ultrasound System
P20 Elite
Thyroid Shield
Standard Thyroid Shield
X-Ray QA Meter
Piranha CT

Print article



view channel
Image: The emerging role of MRI alongside PSA testing is redefining prostate cancer diagnostics (Photo courtesy of 123RF)

Combining MRI with PSA Testing Improves Clinical Outcomes for Prostate Cancer Patients

Prostate cancer is a leading health concern globally, consistently being one of the most common types of cancer among men and a major cause of cancer-related deaths. In the United States, it is the most... Read more

Nuclear Medicine

view channel
Image: The new SPECT/CT technique demonstrated impressive biomarker identification (Journal of Nuclear Medicine: doi.org/10.2967/jnumed.123.267189)

New SPECT/CT Technique Could Change Imaging Practices and Increase Patient Access

The development of lead-212 (212Pb)-PSMA–based targeted alpha therapy (TAT) is garnering significant interest in treating patients with metastatic castration-resistant prostate cancer. The imaging of 212Pb,... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.