Fluorescence Imaging Agent Enables Real-Time Assessment of Gastric Motility

A new fluorescence-imaging agent is designed to enable real-time quantitative measurements of gastric motility in animal models, thereby enabling rapid and effective assessment of a wide variety of related diseases and drug effects in preclinical research and drug development.

VisEn Medical, Inc. (Woburn, MA, USA), a company focused on fluorescence imaging from research through medicine, announced the commercial launch of its new GastroSense 750 fluorescence agent for imaging gastric motility and related drug effects in vivo. Gastric motility, or the rate of nutrient transport through the gastrointestinal tract, is an established measure of overall gastric health, specific gastric disorders, and general physiologic health related to toxicity profiles of systemic drugs.

"The new GastroSense 750 agent represents another robust biologic imaging addition to VisEn's leading suite of agents and fluorescence tomographic [FMT] systems,” said Kirtland Poss, president and CEO of VisEn. "These new fluorescence imaging approaches are providing dramatically improved solutions for measuring key aspects of disease progression and drug response in vivo, and we are looking forward to expanding these areas further with our customers and partners.”

VisEn's proprietary fluorescence imaging agents and labels are designed to provide a very broad and robust range of biologically specific imaging readouts. VisEn offers over 30 different fluorescence molecular agents for imaging key disease-associated biologic targets, processes, and pathways.

All VisEn agents and labels are designed for in vivo biomarker quantification using VisEn's fluorescence molecular tomography (FMT) imaging systems, or for general use along with other nonquantitative fluorescence in vivo imaging systems. VisEn agents are also designed to enable complementary in vitro biomarker readouts in cells and tissues using standard fluorescence microscopy and cellular-based imaging systems. With a focus on translational research and results, all of VisEn's technologies are designed to generate translational data linking preclinical research into clinical medicine.

VisEn's in vivo fluorescence imaging technologies, including its red fluorescence agent range and its FMT imaging systems, provide robust fluorescence molecular imaging performance in identifying, characterizing, and quantifying ranges of disease biomarkers and therapeutic efficacy in vivo. VisEn's FMT systems and agents are used by leading research institutions and pharmaceutical companies worldwide in applications including oncology, arthritis, cardiovascular disease, skeletal disorders, and pulmonary disease. The company also works with large pharmaceutical and clinical partners to design ranges of customized molecular imaging agents and applications designed for their specific preclinical and clinical research areas.

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