We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
CIRS

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

MRI Helps Create Personalized Brain Temperature Maps

By MedImaging International staff writers
Posted on 20 May 2021
Print article
Image: Metabolic heat (a), cerebral blood flow (b) and model-predicted brain temperature (c) in three volunteers (Photo courtesy of Emory University)
Image: Metabolic heat (a), cerebral blood flow (b) and model-predicted brain temperature (c) in three volunteers (Photo courtesy of Emory University)
A new study shows how data from magnetic resonance imaging (MRI) of brain tissue and vessel structure can facilitate personalized brain temperature predictions.

Developed by researchers at the Georgia Institute of Technology (Georgia Tech; Atlanta, GA, USA) and Emory University (Atlanta, GA, USA), the biophysical model can be used to generate 3D thermal distribution maps using whole brain MRI-based thermometry data. The model relies on two fundamental physical principles, conservation of energy and conservation of mass, to predict how heat is generated through metabolism and dissipated via blood flow throughout the brain, via conduction, convection, and advection.

For the study, the researchers first collected structural MRI brain images from three healthy volunteers. After several hours of data analysis and simulations, the biophysical model computed the distribution of brain temperature in the brain, visualized as three-dimensional (3D) maps. To validate the model, the researchers then collected temperature measurements using whole-brain MRI thermometry, compared these measurements to the model’s predictions, and found that they agreed. The study was published on April 15, 2021, in Communications Physics.

“Brain temperature varies throughout the brain as blood flow and metabolic demands change. This means that you cannot assign a single temperature to a brain,” said co-senior author Andrei Fedorov, PhD, of Georgia Tech. “All of the complexity [in the brain’s functioning] results in a very unique personal temperature map that actually tells us a lot about what may be happening to us, what may have happened in the past, or what may happen if we somehow perturb us as a human.”

Despite being only a fraction of the human body’s mass, the brain accounts for 20% of total oxygen consumption in resting conditions, which is used for neuronal metabolism, neural processes, and the functioning of glial, endothelial, and epithelial cells. All this energy is transformed into intense heat production. The brain is also exceptionally well vascularized, receiving 15–20% of total cardiac output, which also serves as the means to remove the heat continuously generated through brain metabolism and neurological function.

Related Links:
Georgia Institute of Technology
Emory University



Print article
Sun Nuclear
Radcal

Channels

Radiography

view channel
Image: CE-marked and FDA-cleared ExacTrac Dynamic enables the delivery of precision radiotherapy (Photo courtesy of Brainlab)

Next-Gen Technology Enables Precision Radiotherapy with “On-The-Fly” X-Ray Confirmation

Deep Inspiration Breath Hold (DIBH) is a well-established technique and standard of care in treating breast cancer with radiation therapy. When a patient takes a deep breath, the distance between the heart... Read more

Ultrasound

view channel
Image: Resona I9 ultrasound system features innovative design elements (Photo courtesy of Mindray)

Mindray’s Latest Resona I9 Ultrasound System Provides Innovation-Driven Experience

Mindray (Shenzhen, China) has launched a new ultrasound system which provides an entirely new experience, driven by innovation to address today’s clinical challenges. Mindray’s latest Resona I9 ultrasound... Read more

Imaging IT

view channel
Illustration

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more

Industry News

view channel
Image: Global diagnostic imaging market is driven by technological advancements (Photo courtesy of Pexels)

Global Diagnostic Imaging Market to Surpass USD 33 Billion by 2026

The global diagnostic imaging market is one of the most critical segments of the healthcare sector. Medical imaging helps in early detection and diagnosis of diseases at a stage when they can be easily... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.