New Approach to Diagnose Sinusitis Could Reduce Antibiotic Use

A new method of diagnosing sinusitis offers the potential to reduce the use of antibiotics and the costs of the disorder to society. Sinusitis is a very common disease and exists in both an acute and a chronic form. In Europe, over 9% of the population suffers from chronic sinusitis.

The author of the research, in the form of a thesis paper, is Pernilla Sahlstrand Johnson, a PhD student, and ear, nose, and throat doctor at Lund University (Lund, Sweden) and Skåne University Hospital (Malmo, Sweden). In the work on the thesis, she and her colleagues at the faculty of engineering at Lund University evaluated a new method to better diagnose sinusitis. The method employs a Doppler ultrasound sensor, which, unlike a normal ultrasound or computed tomography (CT) scan, can determine the viscosity of the sinus fluid. Until now, the only way to find this out for certain has been by flushing out the maxillary sinuses, which is an unpleasant procedure for the patient.

Only patients with thick sinus fluid are considered to need antibiotics, while for those with thin fluid there are other effective treatment options. “Antibiotic resistance is seen as a growing problem. One in four people in Sweden takes antibiotics at least once a year, and many of these have been diagnosed with sinusitis. A more accurate diagnosis could reduce the amount of antibiotics prescribed and the right treatment could also reduce costs,” said Dr. Pernilla Sahlstrand Johnson. “We have used the new method in the laboratory with good results. We are planning to trial the Doppler ultrasound sensor in a clinical environment soon, on a number of patients at the Ear, Nose, and Throat Clinic at Skåne University Hospital in Malmö and Lund.”

Dr. Sahlstrand Johnson has also studied the self-perceived quality of life of a group of just over 200 patients awaiting sinus surgery. As well as the Ear, Nose, and Throat Clinics in Skåne, patients at Karolinska and Sahlgrenska University Hospitals (Gothenburg, Sweden) have also completed questionnaires for the study, which is one of the largest of its kind.

Both general questionnaires and questionnaires specific to sinusitis have been used, and the answers shed light on the patients’ perceived quality of life and mental health and their absence from work. The responses indicate high levels of absence patients reported eight 14-days of sick leave in the course of a year resulting from their sinus problems.

“The participants in our study experienced a significant fall in quality of life as a result of their sinusitis, greater than in other large patient groups with diseases such as angina or cancer. Sinusitis probably also has a major financial impact on society, as it is a common disease and leads to relatively high levels of sick leave,” said Dr. Sahlstrand Johnson.

Related Links:
Lund University
Skåne University Hospital