Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Advantech Europe

Events

18 Feb 2016 - 20 Feb 2016
19 Feb 2016 - 21 Feb 2016
27 Feb 2016 - 03 Mar 2016

Characteristic Sign Allows for MR Diagnosis of Parkinson’s Disease

By Medimaging International staff writers
Posted on 12 May 2014
Print article
Image: A shape similar to a swallow’s tail has been identified as a new and accurate test for Parkinson’s disease. The image, which depicts the healthy state of a group of cells in the subregion of the human brain, was revealed using 3T MRI scanning technology (Photo courtesy of the University of Nottingham).
Image: A shape similar to a swallow’s tail has been identified as a new and accurate test for Parkinson’s disease. The image, which depicts the healthy state of a group of cells in the subregion of the human brain, was revealed using 3T MRI scanning technology (Photo courtesy of the University of Nottingham).
An image similar in shape to the swallow’s tail [a deeply forked tail] has been identified as a new and effective way to diagnose Parkinson’s disease (PD). The image, which depicts the healthy state of a group of cells in a subregion of the human brain, was depicted using 3T magnetic resonance imaging (MRI) scanning technology—conventional equipment currently used in clinical environments.

The research was led by Dr. Stefan Schwarz and Prof. Dorothee Auer, experts in neuroradiology in the School of Medicine at the University of Nottingham (UK), and was conducted at the Queen’s Medical Center (Nottingham, UK) in collaboration with Dr. Nin Bajaj, a specialist in movement disorder diseases at the Nottingham University Hospitals National Health Service (NHS) Trust. The findings were been published April 7, 2014, in the open access academic journal PLOS one. The research builds on a successful collaboration with Prof. Penny Gowland at the Sir Peter Mansfield Magnetic Resonance Center at the University of Nottingham.

The investigators reported that the absence of this imaging sign can help to diagnose PD using conventional clinical MRI scanners. Diagnosing Parkinson’s, up to now, has been clinically uncertain. Diagnosing patients had to rely on expensive nuclear medical techniques. The diagnosis can be problematic early in the course of the condition and in tremor dominant instances. Other nonlicensed diagnostic techniques offer a varying range of accuracy, repeatability, and effectiveness but none of them have demonstrated the required accuracy and ease of use to allow conversion into standard clinical practice.

Using high resolution, ultra-high field 7T MRI technology, Nottingham research scientist had targeted the telltale pathology of Parkinson’s with structural alterations in a small area of the mid brain known as the substantia nigra. This new study has shown that these changes can also be identified using 3T MRI technology, which is accessible in hospitals across Europe and the United States. They subsequently termed the phrase the “swallow tail appearance” as an easy recognizable sign of the healthy appearing substantia nigra, which is lost in Parkinson’s disease. A total of 114 high-resolution MRI scans were reviewed and in 94% of patients the diagnosis was effectively made using this technique.

“This is a breakthrough finding as currently Parkinson’s disease is mostly diagnosed by identifying symptoms like stiffness and tremor. Imaging tests to confirm the diagnosis are limited to expensive nuclear medical techniques which are not widely available and associated with potentially harmful ionizing radiation. Using magnetic resonance imaging [MRI] we identified a specific imaging feature which has great similarity to a tail of a swallow and therefore decided to call it the ‘swallow tail sign.’ This sign is absent in Parkinson’s disease,” Dr. Schwarz concluded.

Related Links:

University of Nottingham



Print article
PHS Technologies

Channels

Radiography

view channel

No Proof That X-ray Radiation Causes Cancer

The widespread belief that radiation from X-rays can cause cancer is based on an invalid paradigm for estimating low-dose radiation exposure risk, according to a new study. According to researchers at Loyola University Medical Center (Maywood, IL, USA), the linear no-threshold (LNT) model, which is constantly used today... Read more

Ultrasound

view channel
Image: The Verathon BladderScan Prime (Photo courtesy of Verathon).

Portable Ultrasound Device Quantifies Bladder Volume

A new portable three-dimensional (3D) ultrasound instrument helps reduce catheter-associated urinary tract infections (CAUTI) by reducing the use of catheters. The Verathon BladderScan Prime is a noninvasive... Read more

Nuclear medicine

view channel
Image: The SiPM detector (Photo courtesy of Volkmar Schultz, Aachen University).

New Hybrid PET/MRI System Developed for Enhanced Breast Cancer Imaging

A novel imaging technique is being developed that can improve breast cancer detection and characterization, and help clinicians evaluate the response of the cancer to treatment. The 4-year project,... Read more

General/Advanced Imaging

view channel

Healthcare IT Manufacturer and Teleradiology Interoperability Expert Introduce New FHIR System

A new interoperability system that was launched at the 2015 Radiological Society of North America (RSNA) annual meeting in Chicago, USA, in November, 2015, is now being introduced into the market. The system enables seamless integration of third party enterprise imaging systems using the latest Fast Healthcare Interoperability... Read more

Imaging IT

view channel
Image: Photo of the virtual reality device mobile diagnostic imaging (Photo courtesy of RSNA).

Prototype of Virtual Reality Device with Potential for Diagnostic Imaging Presented

A prototype of a high-resolution mobile Virtual Reality (VR) diagnostic imaging device for radiologists was presented at the annual Radiological Society of North America (RSNA 2015) meeting in Chicago (IL, USA).... Read more

Industry News

view channel

Radiology Oncology Surgical Robot Devices Sector Could Reach USD 7.3 Billion by 2022

A new report has been published indicating that worldwide market for radiology oncology surgical robots market is growing mainly due to an aging world population, and the benefits the new technology can offer. Radiology oncology surgical robot technology provides opportunities to change cancer treatment methods, including... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.